The story begins in Natchi, a
small town in Kerala, India. American
George States (Jeff Doucette) is
suffering from the last stage of brain
cancer and has only six months to live.
To prevent death and gain immortality,
he decides to extract the
'Nagmani' from a nagin, a
shape-shifting cobra that can change
into a human. He and hired henchmen
capture the nag (the male snake) so that
the nagin (the female) comes after the
capturer to free her mate, thus allowing
him to obtain the nagmani by force. He
keeps the nag in a glass box where he
electrocutes and tortures him. His plan
works and the nagin starts following
them.
The nagin
transforms into a beautiful woman
(Mallika Sherawat), and is later helped
by police inspector Virkram Gupta
(Irrfan Khan) and his wife, Maya (Divya
Dutta), who is infertile, causing a
strain in their relationship. The nagin
helps a few women who are helpless: One
who is beaten mercilessly by her
husband; one being raped by a man, and
so on. She even helps herself when two
men try to rape her. She turns into a
cobra twice the size of a human and
brutally kills those two men, some of
George States’ henchmen who were
involved in the capture of her mate as
well as men who torture women. She turns
back into a human after her killings.
Inspector Gupta tries to help the nagin
find her mate, but at the same time,
tries to investigate the murders,
unaware she is responsible for them.
Finally, the Nagin reaches George's
hideout where she reclaims her mate and
they have sex, leading her to becoming
pregnant. George attempts to capture the
nagin during intercourse since this is
when she will be at her most
vulnerable.
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